INDUCTIGRAFT
Enhanced Bone Growth
With enhanced micro and macro porosity and ideal silicon content shown to be optimal for bone formation, INDUCTIGRAFT is designed to promote early vascularization, increase cellular activity, and enhance bone growth as demonstrated in in-vitro and in-vivo pre-clinical studies.1,2,3,*
*Preclinical data. Results may not correlate to performance in humans.
Mechanism of Action
Learn more about how INDUCTIGRAFT works.
Additional Product Benefits
Enhanced Performance
INDUCTIGRAFT achieves fusion rates on par with autograft—the gold standard in bone fusion. 4,5,6,*
*Preclinical data. Results may not correlate to performance in humans.
Versatility and Ease of Use
The precise handling characteristics of INDUCTIGRAFT allow the product to be molded into multiple shapes to adapt to various surgical needs when using as standalone, with autograft, or bone marrow aspirate.1
Enhanced Porosity
The interconnected and open porous structure of the silicate-substituted calcium phosphate phase of INDUCTIGRAFT is similar to human cancellous bone and is designed to promote enhanced bone growth.2
INDICATIONS FOR USE
- Bone graft substitutes are intended to be used in place of corticocancellous, or cancellous allograft or autograft bone.
- The mechanical environment for such uses experience either low load requirements or compression.
Typical surgical applications for bone graft substitutes are:
- Spinal fusion, where pedicle screw fixation or an interbody cage device is used to relieve the graft site from physiological loads,
- Small void filling, e.g. after removal of a small bone tumour or following bone fracture reduction or in osteotomies, plastic surgery and dental applications.
- It is not intended to be used in place of cortical strut allograft bone where high tensile, torsion and/or bending strength are required. The products are used by surgeons in place of allograft bone (bone from humans stored in bone banks).
RISKS AND WARNINGS
INDUCTIGRAFT should not be used where it could be subject to tension, torsion, compression, shear or bending. A conventional implant (e.g. screw, rod) can protect the graft from such loading actions.
- INDUCTIGRAFT should not be used in volumetrically unconstrained sites (so the graft material cannot move or escape)
Do not overfill or attempt to pressurize the bony defect site, as this may lead to extrusion of the product beyond the site of its intended application and damage to the surrounding tissues, or may lead to fat embolization or embolization of the product into the bloodstream.
- Patient metabolism may compromise bony regeneration
CONTRAINDICATIONS
- Impaction grafting for failed total hip or knee arthroplasty
- Direct load bearing of graft material i.e. In the absence of conventional implants, such as screws and rods
- Infection
- Inability to cover or deliberate non-coverage of graft site using soft tissue
- Avascular or compromised vascular network sites
- Avoid use in patients where in the surgeon’s opinion patient lifestyle, compliance and/or physical attributes would compromise clinical outcome
- Medication which could slow bone healing
CE 0086